Why is Victoza So expensive ? A recent worldwide study that was carried out in thirty various countries found that forty-five percent of the world’s
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Victoza® contains the active drug liraglutide, which belongs to a class of drugs called glucagon-like peptide-1 agonists, or GLP-1. It is prescribed as a liquid solution in a multi-dose, prefilled pen. Liraglutide can also be found in Saxenda.
The Food and Drug Administration approved Victoza in 2010 for adults with type 2 diabetes and extended approval to include use in children ages ten years and older with type 2 diabetes in 2019. It is the first non-insulin drug approved since 2010 for use in children with type 2 diabetes.
Victoza® Mechanism of Action
Victoza® (liraglutide) is an analog of human GLP-1, acts as a receptor agonist. It increases intracellular cyclic AMP, leading to insulin release in the presence of elevated glucose levels.
GLP-1 is a glucagon-like peptide-1 receptor agonist that lowers glucose in patients with type 2 diabetes, obesity, and cardiovascular disease. GLP-1 agonists, also called incretin mimetics, activate the GLP-1 receptor in the pancreas, eliciting insulin output. These receptors can also be found in medications such as Ozempic, Trulicity and Wegovy.
GLP-1 medications help to:
- Enhance insulin secretion
- Suppress glucagon secretion
- Suppress the appetite
- Promote an increase in beta cells in the pancreas
Victoza® for
Type 2 Diabetes in Adults
Victoza is FDA approved to improve blood sugar levels in those with type 2 diabetes in combination with diet and exercise. When you have type 2 diabetes, your body doesn’t respond well to insulin. Insulin brings glucose into your cells from your bloodstream; when you have diabetes, the sugar doesn’t move into the cells leading to elevated levels of sugar in your blood. Victoza helps to lower your blood sugar level by increasing insulin released into the bloodstream, preventing the liver from releasing more glucose into the blood, and slowing down the release of sugar after you have eaten.
Victoza® for Type 2 Diabetes and Heart Disease
Victoza is FDA approved to reduce the risk of major cardiovascular events in adults with type 2 diabetes and heart disease. These events include heart attack, stroke, and cardiovascular-associated death.
Victoza® for Children with Type 2 Diabetes
Victoza is FDA approved to improve blood sugar levels in children ten years of age and older with type 2 diabetes.
Victoza® Dosing Information
The initial dose of 0.6 mg subcutaneously once daily for one week to reduce gastrointestinal symptoms. Note that this is not an effective dose for glycemic control. After the first week, the dose should be increased to 1.2 mg subcutaneously once daily. If needed, the dose may be increased to 1.8 mg subcutaneously once daily.
Follow the dosing and administration directions on your prescription label, medication guide, and instruction sheet. Please speak to your doctor or pharmacist with any questions or concerns. Victoza is a prefilled injection pen injected under the skin with or without food. Victoza should be injected into a different place each time it is administered. Do not change your dose or medication schedule without discussing it with your physician.
Store unopened injection pens in the refrigerator, and do not freeze Victoza. If it should become frozen, discard the medication. After your first use, you may keep in-use pens in the refrigerator or at room temperature and use them within thirty days.
Using Victoza®
If you have been prescribed Victoza, take it as directed by your physician and pharmacist and according to the directions on the prescription label. It should be injected under the skin once a day using the prefilled injection pen. Use disposable needles only once, following state or local laws about discarding used needles and syringes. Use a puncture-resistant sharps container and keep it out of the reach of children and animals.
Possible Side Effects of Victoza®
Like most other drugs, Victoza can cause minor and serious side effects. Depending on age, health conditions, and other medications, side effects will vary. Seek emergency medical attention if you have indications of an allergic reaction to Victoza, including hives, rapid heartbeat, dizziness, problems with breathing or swallowing, and swelling in the face, lips, tongue, or throat.
Call your physician immediately if you experience the following:
- Racing or pounding heartbeat
- Sudden mood or behavioral changes or thoughts of suicide
- Severe and continuous nausea, vomiting, or diarrhea
- Signs of thyroid tumor including swelling in your neck, problems with swallowing, a hoarse voice, and shortness of breath.
- Signs of gallbladder problems such as fever, abdominal pain, clay-colored stool, yellowing of skin or eyes
- Signs of pancreatitis including upper abdominal pain that spreads to the back, nausea, and rapid heart rate.
- Signs of low blood sugar such as extreme fatigue or weakness, confusion, tremors, sweating, rapid heart rate, difficulty speaking, nausea, rapid breathing, fainting, and convulsions
- Kidney problems including painful or difficult urination, feet or ankle swelling, fatigue, and shortness of breath.
Other side effects may occur. Call your physician for medical advice regarding side effects and report them to the FDA at 800-FDA-1088.
Drug Interactions
As Victoza can slow digestion, it may take longer to absorb oral medications. Discuss your current medications with your physician, especially if you take insulin or oral diabetes medication. Other drugs may interact with liraglutide, including prescription and OTC medications, vitamins, and herbal products.
Some interactions can affect how effective a drug is or increase side effects. Before starting Victoza, discuss your prescription, OTC, and supplements with your physician and pharmacist. Victoza, combined with certain diabetes drugs, can increase the risk of hypoglycemia, including:
More Information
What is Victoza used for Once-daily injections of the diabetic drug Victoza (liraglutide) reduce blood sugar and cardiovascular risk. Taking Victoza stimulates beta cells in
FULL PRESCRIBING INFORMATION FULL PRESCRIBING INFORMATION: CONTENTS* WARNING: RISK OF THYROID C-CELL TUMORS INDICATIONS AND USAGE DOSAGE AND ADMINISTRATION 2.1 Important Administration Instructions 2.2 General
Frequently Asked Questions About Victoza®
Victoza is not insulin but can be taken alongside long-acting insulin. They must be taken as separate injections and should never be mixed. Victoza may be taken alone or in combination with common oral type 2 diabetes medications, including biguanides (metformin), sulfonylureas (Sus), and thiazolidinediones (TZDs).
No. Do not take Saxenda and Victoza together, as they contain the same active ingredient.
If you miss a dose of Victoza, skip the missed dose and take the next scheduled dose.
Never share your injection pen, cartridge, or syringe, even with a new needle. This can cause disease or infections to spread.
Victoza is intended to be a long-term treatment as long as you and your doctor determine it is safe and effective.
No. While both medications belong to a class of drugs called glucagon-like peptide-1 agonists (GLP-1), they are different. Victoza contains liraglutide. Trulicity contains dulaglutide. They have both been approved by the FDA to improve blood sugar levels in adults with type 2 diabetes along with diet and exercise. However, Victoza is also used to reduce the risk of major cardiovascular events like heart attack and stroke and, as such, is approved for use in adults with both type 2 diabetes and heart disease. Victoza has also been approved to improve blood sugar levels in children ages ten and older with type 2 diabetes.
Both Saxenda and Victoza contain liraglutide, but they have different uses. Saxenda is used along with diet and exercise to control weight, but it is not used in treating diabetes. You mustn’t use Saxenda and Victoza together.
Alcohol consumption while taking Victoza can increase your risk of hypoglycemia or low blood sugar. This occurs as alcohol blocks the liver from releasing glucose when blood sugar levels are low. If you consume alcohol, discuss the safety and amount of alcohol you drink while taking Victoza.
Using more than the prescribed dosage of Victoza can lead to serious side effects. Symptoms of an overdose include severe nausea and vomiting. If you believe you have taken too much Victoza, call your physician or the American Association of Poison Control Centers at 800-222-1222. Call 911 or go to the nearest emergency center if you are experiencing severe symptoms.
Victoza is not currently advised for pregnant women. Diabetes in pregnant women is treated with other medications.
Victoza starts working within several hours after your first dose. However, it may take up to four weeks to see the full effects on your blood sugar levels.
No. While there has been research on the effectiveness of Victoza on type 1 diabetes, it is not currently approved by the FDA to treat the condition.
Yes, you may need to take insulin or other diabetes medications with Victoza if it is not effective enough to improve your blood sugar levels on its own. Discuss your blood sugar levels and the need for your mealtime insulin with your physician. Don’t stop taking insulin or other diabetes medications unless directed by your physician.
Victoza may be taken any time of the day, but it’s important to choose the same time each day for your injection and remain consistent.
No, Victoza is not known to cause weight gain. Discuss your concerns with weight gain with your physician, as they can recommend the appropriate diet and exercise tips to maintain a healthy weight.
Victoza should not be taken by anyone with:
- a history of hypersensitivity to Victoza or its ingredients
- multiple endocrine neoplasia syndrome type 2
- a personal or family history of medullary thyroid cancer
Victoza stays in the body for about fifty-two to sixty-five hours, but the effects of the drug do not last for this entire period.
The active drug in Victoza, liraglutide, has been prescribed off-label for PCOS to help reduce weight and ease other PCOS symptoms.
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